BRUCINE ALKALOID NF

Brucine, a weak alkaline indole alkaloid, is one of the main bioactive and toxic constituents of Nux-vomica. Modern pharmacology studies and clinical practice demonstrate that brucine possesses wide pharmacological activities, such as anti-tumor, anti-inflammatory, analgesic, and the effects on cardiovascular system and nervous system, etc. However, its central nervous system toxicity severely limits its clinical application. Herein, the physicochemical properties, pharmacological activities, and toxicity of brucine were reviewed, and the novel strategies to address the toxicity issues were discussed, aiming to bring new insights into further research and application of this active component.
Brucine Alkaloid is bitter poisonous alkaloid resembling strychnine and obtained from the tree Strychnos Nux-vomica Linn. It is used mainly in the denaturation of alcohol. Therapeutic uses as Denaturant..
 
Chemical Name:- 10,11-Dimethoxy Strychnine.
Molecular Formula:-C23H26N2O4
Molecular Weight:-394.45
 
Market Potential Area:
United States, China, Germany, Japan, France, Switzerland